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You are here: Home / Open Threads / Damnit to Hell

Damnit to Hell

by John Cole|  June 8, 20055:47 pm| 5 Comments

This post is in: Open Threads

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This is not good:

How does Cafestol, an ingredient in unfiltered coffee raise cholesterol?

The coffee diterpene cafestol (CAF) is present in unfiltered coffee brews such as Scandinavian boiled, Turkish and cafetiere coffee. CAF is the most potent cholesterol-elevating compound known in the human diet. A study by Marie-Louise Ricketts of Baylor College of Medicine sought to determine whether CAF exerts its effects via nuclear hormone receptors that control genes involved in cholesterol homeostasis.

To answer this question, both in vitro and in vivo studies were performed, and the data determined that CAF acts as an agonist ligand for both FXR and PXR, and this may contribute to its ability to raise cholesterol levels. CAF acts as a potential agonist ligand for both FXR and PXR, and this may contribute to its effect on cholesterol homeostasis.

I love my Bodum. You scientists can’t have it.

Here is another link in English:

The type of coffee you’re drinking Wednesday morning could be affecting your cholesterol level.

A new study has found a compound called Cafestol that suppresses a gene that helps breakdown cholestorol in your body.

Cafestol is found in unfiltered coffees like French press coffees, Scandinavian boiled and Turkish coffee. Researchers say that it can be removed using a paper filter.

At any rate- hands off my French Freedom Press.

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Reader Interactions

5Comments

  1. 1.

    Hokie

    June 8, 2005 at 6:06 pm

    Wow. I don’t know enough biochem to even begin to try to parse that.

  2. 2.

    Hokie

    June 8, 2005 at 6:15 pm

    Hrm, so the next question would seem to be how this affects HDL and LDL cholesterol…are both now not suppressed? Does it just lead to an increase in HDL?

  3. 3.

    Kimmitt

    June 8, 2005 at 9:04 pm

    I guarantee you this doesn’t matter if you drink a couple cups a day or less. If you’re drinking more than that, you’ve got other issues far more pressing. Like your bladder, presumably.

  4. 4.

    Toren

    June 9, 2005 at 12:12 am

    I drink around 20 to 30oz a day of French (Freedom) press coffee that you could stand a spoon up in, and my last cholesterol test (March) was 180.
    I say we wait for more data.

Comments are closed.

Trackbacks

  1. BlogBites says:
    June 8, 2005 at 10:24 pm

    At any rate- hands off my French Freedom Press.

    Damnit to Hell

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