The Biden administration plans to urge all Americans to get a booster shot for the coronavirus this autumn to counter a new wave of infections, a White House official said https://t.co/D8NY90tTa7
— Reuters (@Reuters) August 21, 2023
… The official said that while the Centers for Disease Control and Prevention are reporting an increase in infections and hospital admissions from the virus, overall levels remain low.
On Thursday, Moderna (MRNA.O) said initial data showed its updated COVID-19 vaccine is effective against the “Eris” and “Fornax” subvariants in humans.
Moderna and other COVID-19 vaccine makers Novavax (NVAX.O), Pfizer (PFE.N) and German partner BioNTech SE (22UAy.DE) have created versions of their shots aimed at the XBB.1.5 subvariant.
Pending approval from health regulators in the United States and Europe, the companies expect the updated shots to be available in the coming weeks for the autumn vaccination season.
The NYTimes tends to be *very* cavalier about pandemic risks, but still:
… There is a dearth of data on Covid outcomes, including what proportion of people with repeat infections go on to develop longer-term complications, said Dr. Marc Sala, co-director of the Northwestern Medicine Comprehensive COVID-19 Center. But here’s what we know so far.
The severity of repeat infections
For many people who get Covid multiple times, subsequent infections will be as mild as or milder than their first, emerging data shows, likely because of partial immunity from previous infections, vaccination and the fact that the latest circulating variants generally cause less severe symptoms. There are a few exceptions — notably, among some people who are immunocompromised, older or had particularly severe previous infections. People who had a severe first infection are more likely to end up hospitalized or to require medical attention for a reinfection, said Emily Hadley, a research data scientist at RTI International who studies long Covid.Reinfection and long Covid
The chances you will get long Covid from a reinfection are fairly unpredictable — several experts interviewed for this story used the metaphor of Russian roulette. The milder your symptoms, the less likely you are to get long Covid, said Dr. Peter Chin-Hong, an infectious disease specialist at the University of California, San Francisco. But every time you get infected, no matter the severity, there is always a chance that you can develop longer-term symptoms.A buzzy paper that was published in Nature Medicine last fall showed that people with two or more Covid infections were more than three times as likely to develop lung and heart issues, and over 1.5 times as likely to have a neurological disorder, including brain fog and strokes, than those who were only infected once. The study used data collected from U.S. Department of Veterans Affairs health care centers, which meant the participants tended to be older than the general population, and overwhelmingly male. But it showed, in pretty stark terms, that multiple infections are worse than one, said one of its authors, Dr. Ziyad Al-Aly, the chief of research and development at the V.A. St. Louis Healthcare System.
Dr. Sala said he frequently sees patients who were more or less fine after their first couple of infections wind up with long Covid in the wake of a third or fourth infection…
OK, so now what?
It’s easy to feel a sense of fatalism about reinfection, said Dr. Davey Smith, an infectious disease specialist at the University of California, San Diego. But he stressed that you can reduce your risk with common-sense measures like eating dinner outside while the weather’s warm and not hanging out with friends when they’re feeling sick…He also noted that there are ways to lower the risk of long-term complications from Covid: An updated vaccine, which can help buffer against reinfection, will be available this fall, and antivirals like Paxlovid may reduce the risk of developing long Covid…
US govt awards $1.4 bln for development of new COVID therapies, vaccines https://t.co/5auexw69Y8
— Reuters Health (@Reuters_Health) August 23, 2023
August 17th update (Biobot): US community spread is back up to "high" with an estimated 610,000 daily new infections.
Similar levels in all 4 US regions.
🔸610,000 new infections/day⬆️
🔸1 in every 550 new people were infected today
🔸1 in every 55 people currently infected pic.twitter.com/SusI25KCAR— JWeiland (@JPWeiland) August 17, 2023
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At a minimum, I feel it must be at least somewhat more transmissible than the background variants to pop up with 6 sequences in short succession across different parts of the world. The million dollar question is… how much more?
— JWeiland (@JPWeiland) August 20, 2023
The World Health Organization and the U.S. Centers for Disease Control and Prevention are tracking a new, highly mutated lineage of the virus that causes COVID-19. https://t.co/hKlLlfGnrl
— Reuters Health (@Reuters_Health) August 19, 2023
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Japan: EG.5 "somewhat more infectious" than prior strains.
According to the WHO, EG.5 accounted for 21.1% of infections worldwide between July 24th and 30th.
The World Health Organization recently designated EG.5 as a "variant of interest."https://t.co/wUKvjkcoZ2
— CoronaHeadsUp (@CoronaHeadsUp) August 21, 2023
While governments pretend that COVID has gone away, death data tell a different story. Australia has had 5,589 COVID deaths & 194 flu deaths so far in 2023. The death rate from COVID is 28 times higher than the death rate from flu. How much longer will Australia remain in denial? pic.twitter.com/eEqWwZLsgN
— Prof Kathy Eagar (@k_eagar) August 21, 2023
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From the article: “The profile of the infected person that continues to reach hospital emergencies and primary care centers (CAP) is that of a old person, with chronic pathologies, which is decompensated by the mixture of covid-19 and heat” —
Spain: Catalonia has almost 500 hospitalized for Covid.
“500 admitted in the middle of summer is worrying.”https://t.co/DPoVi9MsrN
— CoronaHeadsUp (@CoronaHeadsUp) August 22, 2023
France: Covid incidence rate rises 24.6% in one week.
"Between July 31 and August 6, the incidence rate of the virus was 7.7 per 100,000 population, an increase of 24.6% compared to the previous week,"https://t.co/OcdgQVy7oD
— CoronaHeadsUp (@CoronaHeadsUp) August 19, 2023
UK releases first risk assessment for new COVID variant BA.2.86 pic.twitter.com/kCCWbTd00u
— BNO News (@BNOFeed) August 19, 2023
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A bit surprised at the venue, but this (long) essay appraising the SARS-CoV-2 origins debate is a spectacular dismantling of the lab leak hypothesis https://t.co/62Jue0mtrd
— Dr. Angela Rasmussen (@angie_rasmussen) August 19, 2023
I don’t particularly trust Quillette‘s editorial board either, but it’s worth reading the whole thing:
… Some lab-leak sympathisers were simply persuaded by the presence of a virology lab in Wuhan and considered the question no further. Others embraced the hypothesis because they loved Trump (or rejected it because they hated him). Some liked it because (for a long list of very good reasons) they despise and distrust the CCP. Others just want to see Anthony Fauci’s head on a pike, either because he recommended social restrictions to control the pandemic or because he was unable to stifle a smirk during one of Trump’s incoherent press conferences (or both). Some decided that public-health authorities and other experts are simply credentialed frauds who had screwed the pooch on public masking and various other aspects of pandemic messaging, thereby forfeiting any reasonable expectation of trust. All allowed themselves to be seduced by a heroic narrative in which humble internet gumshoes, armed only with a laptop and a commitment to the truth, humiliated arrogant elites and exposed a cover-up that reached all the way to the top of the US medical establishment…
The lab-leak hypothesis may also be appealing for a more human reason—just as many people were reluctant to believe that someone as important as Kennedy could be murdered by someone as unimportant as Lee Harvey Oswald, perhaps the search for a human agent who can shoulder the blame for the pandemic relieves us of the idea that we live on a dangerous and chaotic planet, fraught with natural risks we do not yet properly understand and which we are presently powerless to control.
While these may all be compelling reasons to find the idea of a lab-leak appealing, they do nothing to prove that the SARS-CoV-2 virus escaped from a Wuhan lab. The lab-leak hypothesis is not a moral or political matter, it is an empirical question. The answer may have consequential moral and political implications, but first we need to establish what happened. That answer is emerging, albeit more slowly than any of us might like. And when it finally arrives, it will be the product of laborious and painstaking research by people who know what they are talking about, not of investigations by amateur sleuths and agenda-driven activists who don’t.
An inhalable vax: Yale Univ scientists are developing an #mRNA #Covid vaccine made w/ nanoparticles, no shot needed. An inhalable vax in early tests guards against #SARSCoV2 & paves the way to delivering mRNA therapies for other medical conditions this way https://t.co/QRXPvRy3OR
— delthia ricks 🔬 (@DelthiaRicks) August 21, 2023
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People who endured even mild cases of covid-19 are at heightened risk two years later for lung problems, fatigue, diabetes and certain other health problems typical of long covid, according to a new study that casts fresh light on the virus’s true toll.https://t.co/zs8LIQM3ns
— The Washington Post (@washingtonpost) August 21, 2023
(Unpaywalled)
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Cognitive research on #LongCovid needs an overhaul, the NeuroCOVID Internat'l Neuropsychology Taskforce says. Panelists made 3 recommendations to improve life for #LongCovid patients. Problems caused by the disorder include brain fog, which can last months https://t.co/1HAltW9RnS
— delthia ricks 🔬 (@DelthiaRicks) August 20, 2023
Ending the emergency phase of the pandemic has contributed to a drop in genomic surveillance, further reduced willingness to implement mitigation measures, and delayed approval of updated vaccines. Remember that as fall hits.
— T. Ryan Gregory (@TRyanGregory) August 20, 2023
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False claims about racial susceptibility to COVID by RFK, Jr. and others are dangerous and reveal a widespread misunderstanding of our shared vulnerability to disease | Opinion https://t.co/hX2se0vt6m
— Scientific American (@sciam) August 16, 2023
sitting U.S. Senator
up at 1am sharing InfoWars stories
that he found via the account for the COVID conspiracy movie Died Suddenly, which falsely claimed people died from the vax who in reality are still alive
— Matt Binder (@MattBinder) August 19, 2023
"I'm striking a blow for freedom!" Bruh, you're whining because you have to wear a surgical mask for the ten minutes you're in Harris Teeter. Nathan Hale would think you're a huge weenie.
— Gary Legum (@GaryLegum) August 19, 2023
Snark, perfectly pitched to mimic the bad-vaxx sites:
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Reader Interactions
32Comments
Comments are closed.
OzarkHillbilly
Wheeeeeeeeeeee….
NeenerNeener
Monroe County, NY:
20 new cases on 08/16/23.
29 new cases on 08/17/23.
32 new cases on 08/18/23.
24 new cases on 08/19/23.
25 new cases on 08/20/23.
11 new cases on 08/21/23.
22 new cases on 08/22/23.
Deaths now at 2302, only up 1 from last week.
The case counts are still worrying but at least not as many people are dying from/with it.
lee
I am very happy to see that the new boosters are going to be open to everyone.
There is still a third of Americans that believe that the covid vaccine caused thousands of cases of sudden death.
LiminalOwl
I recently started following the substack Your Local Epidemiologist. She has further interesting info on the newest (so far extremely rare) variant: https://open.substack.com/pub/yourlocalepidemiologist/p/a-new-variant-ba286?r=1mqsc&utm_campaign=post&utm_medium=web
I have to acknowledge a wry chuckle for whoever named a variant Eris. (All hail Discordia? Ugh.)
Professor Bigfoot
@lee: Let Mr. Darwin collect his due, then, because fuck those people, really.
Betty
Finally there is a report confirming my theory that Covid caused the onset of my high blood pressure. I also believe it caused my subsequently diagnosed left branch bundle block. The cardiologist curtly dismissed me when I suggested this. That’s what has happened to so many people who had long-term effects from Covid. So frustrating.
Dagaetch
I hope somebody replied to Mike Lee: “Your proposal is acceptable.”
Soprano2
@Betty: I found out I had that last year. The doctor said I could have had it my whole life and not known it. It’s entirely possible Covid caused yours to come to the surface; I think we’re going to spend decades figuring out everything Covid has done to some people who contracted it. I only found out about my left bundle branch block because I had some symptoms that made me believe I might have had a heart attack, so my doctor had me take an EKG; that’s when they found the irregularity. The cardiologist told me I might never have any symptoms from it, unless I develop heart failure. I hope I never have to do that stress test again! Seeing my heart valves working on the ultrasound was cool, though.
I’m not sure what the person who posted that governments are ignoring Covid expects them to do. There is zero appetite at this time for any kind of mask mandates or other Covid measures.
NorthLeft
Thanks again Anne. Keep up the great work. It is appreciated.
From Ontario; my wife and I have gone back to wearing masks in certain venues, like Grocery stores, crowded stores and malls.
Our plan is to get our next booster (our sixth) in the fall, but recent reports are making us reconsider that strategy.
Best wishes to all to stay safe and healthy.
Wvng
Twitter, X, is awash with “no one will force me to wear a mask this time” posts, with hundreds of “right on” comments and thousands of likes. I suspect this means that the republican:democrat ratio of very sick and dying folks will remain high.
lowtechcyclist
@Wvng:
Wait ’til they all get sick from the mRNA that us vaccinated people go around shedding all the time! ;-)
BenCisco
@Wvng: If not for the collateral damage they will do, I’d be fine with this.
dmsilev
I just want to know what exactly “turbo cancer” is.
BR
Are there any updates on when they’re going to make the boosters available? The date keeps bouncing around, and that uncertainty makes it really hard to plan.
Matt McIrvin
@lee: I think the UK is only going to recommend them for over-65s and the unusually vulnerable– the weird Tory “infect everyone and power through it” mindset strikes again.
Jean
We’ve had all the shots here, and as far as we know, neither of us has had COVID. Last Thursday evening, he had dinner with a group of old friends. Someone at the table was infected (unknowingly) at the time, and since then, two from the table of 6 or so, tested positive within two days. We are still negative six days later, but will test again today. Thursday, tomorrow, will be a week since exposure. Could we have escaped??
Matt McIrvin
Monday of last week, we saw “Sweeney Todd” on Broadway starring Josh Groban. Great show. I masked up, hardly anyone else did.
Yesterday I heard Groban caught COVID a couple days later and is out sick for now.
Yarrow
Question – how long do people generally have increased immunity after a Covid infection? Does that change if you’re vaccinated?
Yarrow
@Jean:
Yes. Depends on many factors, like where you were sitting in relation to the infected person. What the airflow was in the area (was it blowing toward the two other people who tested positive?). What your general health is. Are you vaccinated and how recently you’ve been vaccinated.
I don’t know if you remember the public health diagrams from early in the pandemic of seating in a choir rehearsal in Washington state and a restaurant in China. They showed the air flow and how that affected who got sick. In the restaurant there was a window air conditioner that blew air from the infected person across several tables. So people sitting further away but in the line of the a/c got infected, while people closer but not in air flow line did not.
narya
I am really hoping to get the new booster soon. I’m planning to visit my parents and I’m taking the train (sleeping car, so somewhat isolated) to get there. Dad’s bladder cancer has returned, though it’s not clear how quickly it’s moving or how much ground it’s taken over–he does NOT want any more probing, poking, scanning, scraping, etc.–and I’d like to see him in case it’s fast-moving. His 93rd birthday is in a few weeks (I can’t make it for that–aiming for early October), and, between his and my mother’s various ailments, the last thing I want to do is bring them a covid infection. I mostly mask indoors; recently I’ve made exceptions for, e.g., running into the coffee shop for something, but I’ve not been masking outdoors.
Jean
@Yarrow: Thanks, Yarrow.
Audrey
@NorthLeft: I’m also in Ontario, are you reconsidering based on the case numbers? I’m still thinking I’ll wait until fall since I hope those doses might be more effective against the variants which seem more likely to be dominant at that time (although that’s a crap shoot of course.)
I’m very thankful to Anne Laurie for continuing this series as the news influences my decision process.
JBWoodford
@dmsilev: Cancer of the turbo, of course.
(It might be a typo, though, if effluent from vaccinated individuals in SE Asia has been shown to cause cancer in food fish.)
MazeDancer
Thank you, Anne Laurie. No doubt, it is way no fun to keep compiling these reports, but know how much good you are doing.
Those of us who are immuno-compromised, though we are used to being ignored by most of the medical community, feel a bit of comfort from the knowledge you provide.
My heart goes out daily reading tweets from people who have developed Long Covid being completely outraged and devastated that there is nothing to be done for them. That there is going to be nothing, mostly because there is no money in it. And most doctors don’t want to see them,
Welcome to the club, my friends. Not much fun to be had, but at least most of the people with Long Covid are not being constantly told it’s all in your head.
Yarrow
So I got Covid in June. I got pretty sick and was a cautionary tale for my neighbor who had been dragging her feet on getting a booster because the previous vaccines had knocked her out for 24-48 hours. After she saw how sick I was she and her husband got the booster in late June before a trip. The kids didn’t as they were at camp.
Fast forward to August. The whole family had just returned from a visiting other family and the son, who didn’t get the booster, got sick. She tested him and yes, positive for Covid. She talked to all the family they’d just been with and no one was sick. They don’t know how he got it as they are still very cautious and wear masks.
She tested the kids, herself and husband. Husband tested positive but only had a mild cough and congestion for a day or two. Son had fever, congestion, fatigue for several days but bounced back quickly. Other kid tested positive but had no symptoms. She never tested positive but could tell she was fighting something for about 24 hours and then felt fine.
So, verdict on the vaccine you can get now is that it helps against the current strains of Covid. They got the booster in late June, Covid in the house in early August. Of the two adults who got the booster, one never tested positive, the other did but had very mild symptoms for only 24 hours. Vaccines work.
JustRuss
@Matt McIrvin: Friends of mine who are very into theater are saying that many productions in Europe are closing due to the cast getting covid.
Carlo Graziani
Yes, thanks, Anne, for keeping up these timely compilations.
Two points of order:
(1) “Hospitalizations with COVID-19” is not the same thing as “hospitalizations for COVID-19.” Particularly in the modern era of very limited recorded testing due to the advent of home antigen tests, the meaning of COVID-19 hospitalization data has changed from what it was in 2020. It is no longer a pure indication of severe disease, but rather a (biased) sampling of population positivity, selected by hospitalizations for all causes (auto accidents, unrelated disease, etc.) including severe COVID-19. But since the advent and dominance of the Omicron variant in December 2021, severity/virulence of SARS-CoV-2 is greatly decreased, as we know. So that rise in hospitalizations is interesting mostly for what it says about positivity rates, in conjunction with rising rates in sewage data (a more precise indicator), rather than for the increasing disease outcome danger that would have been the conclusion from such data in 2020-21.
(2) There can be no possible doubt that new variant BA.2.86 is more transmissible than existing, prevalent variants. Greater transmissibility is the mechanism by which new variants emerge, grow rapidly in prevalence, and displace previous variants: A new, more rapidly-transmitting variant tears around the host population, alarming immune systems and effectively slamming the door on slower variants. It’s the reason that there are only a small number of effectively circulating variants at a time, and the reason that cases of individual hosts infected by multiple variants are extremely rare. The issue is how much more transmissible it is. It doesn’t yet have a Nextstrain Clade name assignment, which may be the reason that it’s not yet showing up at the covariants.org site. But anecdatally, it appears to be on the rising trajectory that leads to variant displacement within a few months, in which case by late fall almost all infections are likely to be BA.2.86. So the other question is whether its mutations lead to greater virulence/more severe disease. We should know in a few more weeks. Let’s hope not.
dnfree
Thank you again for the updates and for continuing to see this as serious. We still mask in grocery stores (along with a few others) and in public meetings (often as the only ones) even though cases keep occurring in our community.
Chris T.
@dmsilev:
Cancer of the turbo, of course. You can only get it if your car has a turbo.
(oops, beaten)
Chris T.
@Yarrow:
Serious answer for once: nobody knows for sure, but looks like (a) 6 months to a year, and (b) maybe, but nobody knows if it’s longer or shorter on average.
Carlo Graziani
@Chris T.: One clarification: The immune system is a layered set of defenses, not a single mechanism. The layer of the adaptive immune system that declines in potency against SARS-CoV-2 is the antibodies, which are a sort of first line in charge of slowing down the infection’s progress, but which do not clear the virus or prevent severe disease. The latter services are provided by the cellular immune system (killer T-cells and such). Those appear not to decay much, if at all, in effectiveness, and are not fooled by variants—T-cells “trained” on the original variant by a 2020 infection or a 2021 vaccine are still quite capable of clearing out a SARS-CoV-2 infection due to a modern variant. They just have a much more strenuous clean-up job to perform, because it takes them a certain time lag to respond, and meanwhile the declining efficacy of the antibody response has allowed the infection to progress much farther than it would have, had those antibodies been refreshed by a recent vaccination or infection.
Mart
@Wvng: I expect the right will accept a nano particle Covid vaccine with open arms!