More human avian flu cases in Washington state, California
So far 15 of the human cases have been associated with exposure to H5N1-infected poultry, and 20 have been associated with exposure to sick or infected dairy cows.https://t.co/Ev5Bs1Tw4u pic.twitter.com/DKvbprQPuk
— CIDRAP (@CIDRAP) October 29, 2024
H5N1 virus isolated from infected dairy #worker is 100% lethal in #ferrets, but does not appear to be circulating anymore @UWMadison @nature https://t.co/NP9Hhyz9Uw
— Medical Xpress (@medical_xpress) October 28, 2024
A strain of H5N1 avian influenza virus found in a Texas dairy worker who was infected this spring was able to spread among ferrets through the air, although inefficiently, and killed 100% of infected animals in studies University of Wisconsin–Madison researchers performed with the strain earlier this year.
The good news: the dairy worker experienced mild symptoms and fully recovered, and the H5N1 strain that infected the worker does not appear to have continued spreading in the wild…
Kawaoka and his collaborators found that the H5N1 virus that infected the Texas dairy worker included a mutation that the team first identified in 2001 as important for causing severe disease. Luckily, Kawaoka says, the strain with that mutation seems to have died out.
“This isolate is unique among the H5N1 viruses circulating in cows,” he says…
.@USDA confirms another 8 dairy herds in California are infected with #H5N1 #birdflu. That brings CA's total to 186 & the national total to 388, per USDA. (I list Michigan's 30th herd here, which hasn't yet been confirmed by USDA. MI reported it on Oct. 17.)…
— Helen Branswell 🇨🇦 (@HelenBranswell) October 29, 2024
US: California workers resist H5N1 avian influenza testing
"There is a very significant undercount of cases because we don't have a way to monitor who is sick because workers are unwilling to test,"
The Cattle Sitehttps://t.co/phNEMVrVZN
— CoronaHeadsUp (@CoronaHeadsUp) October 25, 2024
Good news for people who’ve been trying to get a booster:
CDC vaccine advisers recommend second COVID vaccine dose for seniors, immune-compromised
The recommendations were made to shore up protection in vulnerable groups and add clarity for patients and health providers.https://t.co/tPZmKB8QYd pic.twitter.com/piLM4neWug
— CIDRAP (@CIDRAP) October 23, 2024
US COVID markers continue to decline
Though the KP.3.1.1 variant is still dominant, levels of the newer XEC variant continue to rise.https://t.co/cXmyIe420d
Photo: NIAID/Flickr cc
— CIDRAP (@CIDRAP) October 25, 2024
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Engineers unveil AI model for predicting, controlling #pandemic spread linked to #airTraffic @SciReports https://t.co/i55GbP2Msa
— Medical Xpress (@medical_xpress) October 24, 2024
A team of engineers at the University of Houston has published a study in the journal Scientific Reports on how international air travel has influenced the spread of COVID-19 around the world. By using a newly developed AI tool, the team identified hotspots of infection linked to air traffic, pinpointing key areas that significantly contribute to disease transmission.
The analyses identified Western Europe, the Middle East and North America as leading regions in fueling the pandemic due to the high volume of outgoing international flights either originating or transiting through these areas…
To understand how air travel affects the spread of infections, Van Nguyen and graduate students Akash Awasthi and Syed Rizvi tested small changes in their model (perturbation analysis) to see how sensitive it is to different factors and examined flight connections between different regions and countries.
This helped them analyze which parts of air traffic have the biggest impact on the spread of the virus and which flight reductions in highly sensitive areas would efficiently reduce predicted global cases…
India: Doctors struggle to treat long Covid patients as researchers point to inadequate studies
"A study by researchers … estimated that 31% of the once-infected people in North America, 44% in Europe, and 51% in Asia, have long Covid."
The Hinduhttps://t.co/p6aUh2j2u6
— CoronaHeadsUp (@CoronaHeadsUp) October 27, 2024
New Zealand: Epidemiologist warns summer wave of Covid-19 approaching
'We can't wish it away', says University of Otago professor Michael Baker.
RNZ Newshttps://t.co/csP2Axy9K1
— CoronaHeadsUp (@CoronaHeadsUp) October 28, 2024
Canadian COVID Forecast: Oct 26-Nov 8, 2024
SEVERE: CAN, BC, MB, NB, North, NS, ON, PEI, QC, SK
VERY HIGH: NL, AB
HIGH: none
MODERATE: noneAbout 1 in 34 people in Canada are CURRENTLY infected. pic.twitter.com/C2VKsZNTkN
— Tara Moriarty (@MoriartyLab) October 27, 2024
Across 7 countries, the incidence and symptom complex of #LongCovid, based on the new @WHO criteria (10 databases, > 3 million people)https://t.co/opCXCEXJCx
— Eric Topol (@EricTopol) October 29, 2024
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Repeated COVID #vaccinations found to enhance mucosal immunity against the virus @sciencetm https://t.co/dVkrUMb5Oj
— Medical Xpress (@medical_xpress) October 23, 2024
During the COVID pandemic, many of us received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.…
Ph.D. student Jozefien Declercq (VIB-UGent) explains, “We found that individuals who received multiple doses of mRNA vaccines exhibited a marked increase in neutralizing antibodies in nasal secretions, which are essential for blocking viral entry. Not only that, but the immune responses generated by mRNA vaccines may persist longer than previously thought, which provides hope for sustained protection against emerging variants of the virus.”
The findings suggest that repeated vaccinations not only bolster systemic immunity but also enhance mucosal antibody responses, providing a more robust defense against the virus…
Paxlovid tied to fewer COVID-19 hospitalizations, reduced risk of long COVID
Paxlovid was associated with a 61% lower risk of hospitalization.https://t.co/4WiSKLp8DQ pic.twitter.com/6UgRXZ3iNI
— CIDRAP (@CIDRAP) October 29, 2024
Does Paxlovid reduce #LongCovid?
A new study says yes, adding to several previous reports with some lack of concordance https://t.co/NKGAKPG0OK pic.twitter.com/qJzwjTvY7Q— Eric Topol (@EricTopol) October 29, 2024
How bots shaped public discourse on COVID.
Study: The Impact of Bots on COVID-19 Health Communication https://t.co/6FP3Gq50FP
"…malicious bots pose a serious threat to public trust and the effectiveness of health messaging."
"…COVID-19 bots predominantly focused on…
— Timothy Caulfield (@CaulfieldTim) October 28, 2024
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Studies show long-COVID symptoms distinct from other respiratory infections, common in Marines
COVID patients were more at risk for seven particular symptoms, including loss of smell.https://t.co/MJ0qRNCNyi pic.twitter.com/7BkQBORIA6
— CIDRAP (@CIDRAP) October 25, 2024
GAO report shows how US schools spent pandemic relief funds, including on better ventilation
Of the schools visited and surveyed, nearly half (48%) said they used the federal relief funds to increase building ventilation.https://t.co/XeC1bbZMDA pic.twitter.com/WAsYMd9tGQ
— CIDRAP (@CIDRAP) October 24, 2024
Long COVID Is Harming Too Many Kids
".. kids are repeatedly exposed to SARS-COV-2 in underventilated schools and parents believe they will suffer no serious harm."
Scientific Americanhttps://t.co/NabxJdaSJR
— CoronaHeadsUp (@CoronaHeadsUp) October 27, 2024
This week’s exotic virus don’t-panic scare:
Iowa reports fatal Lassa fever case in a traveler
Imported cases are rare, and the United States has reported 8 in the past 55 years.https://t.co/yEosZQih8T
Photo: NIAID/Flickr cc pic.twitter.com/lltBhoFFTp
— CIDRAP (@CIDRAP) October 28, 2024
CDC offers new details on Lassa fever case in Iowa
If confirmed, the case in Iowa would be the ninth imported case in the United States since 1959.https://t.co/3c9TVnELXL pic.twitter.com/ghgnaXuTBe
— CIDRAP (@CIDRAP) October 29, 2024
Last week’s Marburg scare seems to have been successfully suppressed:
Rwanda's latest Marburg virus case has links to cave site
The cave where zoonotic spread occurred from bats is in a mining region.https://t.co/9EEoJr1qiA
Photo: NIAID/Flickr cc pic.twitter.com/xaJpRmR4m7
— CIDRAP (@CIDRAP) October 25, 2024
NotMax
Local Costco has resumed offering COVID shots. Dunno if it is system-wide, though. Check your nearest location.
In most (all?) Costcos one needn’t be a member to make use of the pharmacy.
EarthWindFire
We’ll all learn about the next pandemic here. Thank you 1000 times, AL.
eclare
Got my covid booster and flu shot about a week ago. Kroger is giving away a $20 credit on your Kroger card if you get more than one vaccine, so I got paid for something that I was going to do anyway.
TF79
Thanks for compiling these – interesting that US and Canadian cases seem to be moving in opposite directions
Scout211
I read that an additional COVID shot was approved for people 65+ and for those who are immune compromised. From the link  in AL’s OP:
Being in the age 65+ group, we have been getting COVID shots every six months the whole time COVID shots have been available so that doesn’t seem new.  But it’s good that it has been announced.
I had not heard about three or more doses for immune compromised people, though. Â That seems very good.
TBone
@eclare: wow, Kroger is really doing its part to combat vaxx hesitancy, yay!
TBone
@TF79: I don’t see how that’s truly possible…(of course, I could be wrong!) but is the population there doing something we’re not or vice versa?
ETA data collection methods, prolly.
Yarrow
@eclare:Â To clarify Kroger’s $20 incentive – you have to get flu and one other vaccine. It can be tetanus or Covid or any other vaccine but they MUST be given at the same time and one has to be flu.
I got my Covid vaccine over a month ago and then went back for the flu vaccine. They told me when I got the Covid vaccine that they’d put a note on my account so when I got the flu vaccine I could get the $20 and not just the $5 you get for one vaccine. Nope. It doesn’t work that way. You have to get both at once.
My body doesn’t like getting too many vaccines together so I spread them out. Seems a bit unfair to people like me, but oh well. I still got the $5. The $15 difference isn’t that big of a deal.
Kristine
Happy to see news of antibodies showing up in nasal mucosa. Hoping it continues to build over time since I read that a nasally administered vaccine could be expected in 2027 at the earliest.
Apparently survived my first post-pandemic hotel stay unscathed. I did mask in crowded rooms and gathering spots, one of the very few who did so.
New Deal democrat
The news on COVID this week is very good. Both Biobot and the CDC show wastewater counts close to their all time lows. The CDC shows a decline of over 75% from the summer wave’s peak, and 85% below last winter’s peak. All four Census regions are participating.
Deaths for the latest week for final numbers, September 28, were the lowest in nearly two months at 958. The latest preliminary data, for the week of October 19, is 341 deaths, just above the prior week’s 327, and the second lowest preliminary number since August 3, suggesting a final number of about 750-900.
Last Friday’s variant update continued to show the summer’s KP.x variants waning, and XEC increasing to 17%. There’s also a newer variant, MC.1, at 5%. Remember that a big % increase for a lower total number translates into a slow absolute increase, which is good news showing only a wavelet of transmissibility.
In short, we are in the best position yet by far heading into the peak Thanksgiving through New Year’s Day season.
Weftage
(My bold.) Given that 100% mortality rate, I’m now wondering, with some alarm, what an efficient transmission would look like.
jonas
Had scheduled a Covid boost the other day, but was still fighting off an annoying cold, so that got postponed. Blech. Everyone where I work (and the kids at the local school) seems to have caught this (non-Covid) respiratory virus that doesn’t make you really sick, but leaves you with a hoarse voice and lingering cough for weeks on end.
Also, I can’t even with these dairy farmers, whose response to bird flu is “If we don’t test or talk about it, it doesn’t exist! Just like that ‘Covid’ scare a few years back!” These are also the same people who will vote for Trump because of his promise to deport undocumented workers that constitute, you know, the bulk of their workforce. The leopards will definitely spare our faces, they figure.
Scout211
LOL. Â Yeah, that was confusing. Â Having not clicked through to the article, I assumed that it meant many ferrets were exposed but very few of those exposed were infected. But being lazy, I did not click through.
H.E.Wolf
Thank you, Anne Laurie, for continuing to keep us informed and up-to-date.
lowtechcyclist
There were pundits who were complaining for years afterwards about the harm caused to kids by shutting down the schools in 2020-2021. If I could remember which pundits were doing this (I think Yglesias was one, but I’m not sure), I’d be sending them links to this article.
In March and April 2020, there were refrigerator trucks full of bodies parked outside of NYC hospitals. Of course we shut down the schools. We didn’t know jack shit about this plague, other than it was killing lots of people. We wanted to keep our kids safe, knowing full well how easily germs spread in classrooms. And even now, we’re still learning about its long-term effects. Maybe erring on the side of caution is a good idea in general, y’know?
Weftage
@Scout211: Ah, that makes sense. “You probably won’t get this, Friend Ferret, but if you do, it will kill you.”
glc
Long covid:
https://www.nature.com/articles/d44151-024-00168-7 (dementia)
https://www.nature.com/articles/s44161-023-00336-5 (heart)
NHS tightens up recommendations (this seems interesting)
https://www-essexlive-news.cdn.ampproject.org/v/s/www.essexlive.news/news/uk-world-news/nhs-10-day-covid-warning-9649846.amp
Avian flu
https://www.nature.com/articles/s41586-024-08254-7
Mart